This chapter reviews different approaches for the development of new models, architectures and real applications of physical agents. The chapter starts by identifying this kind of agents and their main requirements. After that, it presents one approach to allow deliberation while the world changes, and some specific applications that have been implemented by different participants of the AgentCities.ES network: a multi-agent system architecture to control a single robot, a submarine robot, and a container terminal management system for the port of Valencia.