E-healthcare has acquired great importance in recent years and requires the development of innovative solutions. This paper presents a telemonitoring system aimed at enhancing remote healthcare for dependent people at their homes. The system deploys a Service-Oriented Architecture based platform over a heterogeneous Wireless Sensor Networks infrastructure. Furthermore, the information obtained by telemonitoring systems must be managed by intelligent and self-adaptable technologies to provide an adequate interaction between the users and their environment. In the proposed system, the WSNs platform is integrated with a multi-agent architecture so that information gathered by WSN nodes is managed by intelligent agents with reasoning mechanisms.