This paper presents an intelligent multi-agent system that is aimed at improving healthcare and assistance to elderly and dependent people in geriatric residences and at their homes. The system is based on the PANGEA multi-agent architecture, which provides a high-level framework for intelligent information fusion and management. The system makes use of wireless sensor networks and a real-time locating system to obtain heterogeneous data, and is able to provide autonomous responses according to the environment status. The high-level development of the system that extracts and stores information plays an essential role to deal with the avalanche of context data. In our case, the multi-agent system approach results satisfactorily because each agent that represents an autonomous entity with different capabilities and offers different services works collaboratively with each other. Several tests have been performed on this platform to evaluate/demonstrate its validity.